Best Blastocyst Transfer treatment centre in Delhi, India
Frequently Asked Questions
The blastocyst's most distinguishing feature is that it has reached the phase where the growing baby's own genes have been activated and are taking over the rest of the development. This is referred to as "genomic activation," and because genes are the chemical codes that distinguish us as individuals, genomic activation is the critical stage at which a distinct individual emerges from conception.
Researchers are aware of the fact that conventional IVF technology transfers the embryos into the uterus earlier than was normal in naturally occurring pregnancies. Usually, the embryo stays in the fallopian tube, growing and dividing, and does not reach the uterus until after three to four days of development. Based on this fact Tubal transfer procedures such as gamete intrafallopian transfer (GIFT) and zygote intrafallopian transfer (ZIFT) were developed.
Researchers were unable to establish lab culture mediums and incubation techniques that allowed embryos to mature into blastocysts in the early stages of IVF technology. Advances in embryo culture techniques have since made it possible to develop to the blastocyst stage.
In traditional IVF, embryos are cultivated for two to three days before being placed back into the uterus. The embryo has between four and eight cells inside the shell, or zona pellucida, at this stage of development, and they must develop for another four to five days inside the uterus before becoming blastocyst stage embryos that are ready for implantation.
Yes, blastocyst transfer reduces the chances of multiple births as only embryos that appear to have the greatest opportunity for a successful implant are chosen. This means that only one or two blastocyst embryos are transferred, with pregnancy rates of greater than 50 percent in patients who develop healthy blastocysts. Hence, eliminating the risk of high-order multiple pregnancies, such as triplets or quadruplets.
The development rate of blastocysts is much more suited in the uterus. As a result, equally successful pregnancy with blastocyst transfer is achieved with fewer embryos and a reduced incidence of multiple births.
There is just a couple of days difference between Day 3 and Day 5, however, there is a significant difference between these two stages of maturation. Embryos grow at a very fast pace, the embryo starts as a single cell but will divide every 12 to 24 hours. So, by day 3 of growth, it is between four and eight cells and just two days later, on day 5, an embryo will consist of between 70 and 100 cells. At this stage the embryo is developed as a blastocyst. It consists of two types of cells, those that will develop into fetal tissues, and those that will develop into the placenta. Only about one-third of embryos manage to successfully reach the blastocyst stage of development.
Extending the culture of enlarged blastocysts for a few hours to allow for the transfer of spontaneously hatching/hatched blastocysts increases the implantation and pregnancy rates without increasing the danger of multiple gestations.